Luteolin is a naturally occurring compound found in foods including parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others. Luteolin has antioxidant, anti-inflammatory, anti-allergic, anticancer, and immune-modulating properties to suppress hyperactive immune systems. Luteolin is a potent hypoglycemic agent and improves insulin sensitivity. Luteolin may help promote healthy blood glucose levels and help in weight management for Syndrome X. Externally luteolin can be used for skin allergic/inflammatory disorders and for skin cancer prevention. Luteolin is a promising agent for use in ophthalmology: for prevention and treatment of cataract and of vascular eye disorders. Luteolin is an active inhibitor of different hyaluronidases, which modify hyaluronic acid. Hyaluronic acid, a heteropolysaccharide, is one the polymers that accounts for the toughness and flexibility of cartilage and tendon.